1-乙酰乙酰基-3-甲基吲哚对稀土离子能量传递过程研究

通过1-乙酰乙酰基-3-甲基吲哚(I3MK)与各种稀土离子在77K乙醇刚性溶液体系中的荧光光谱、磷光光谱的测定,进行了I3MK向稀土离子能量传递过程的静态分析;从I3MK和I3MK-Tb(Ⅲ)体系的荧光寿命、磷光寿命、量子产率,时间分辨光谱等,计算了各主要能量传递过程的速率常数和能量传递效率,进行了该体系能量传递过程的动态分析,提出了Perrin公式的修正参数,讨论了I3MK-Tb(Ⅲ)体系的能量传递机理.     

Production of an antiproliferative furanoheliangolide by Lychnophora ericoides cell culture

This work reports for the first time the production a furanoheliangolide (goyazensolide) by plant cell culture. Monitoring of the goyazensolide metabolism revealed that the maximum production occurred during the lag phase of the Lychnophora ericoides callus culture. The antiproliferative activity of obtained goyazensolide was evaluated against seven cancer cell lines using MTT assay. The results revealed a potent cytotoxic activity for the furaheliangolide with IC50 values in the range of 0.06 microg/ml for CEM leukemia cells to 0.75 microg/ml for B16 melanome cells.     

小鼠血清,全血和鼠毛中的元素含量研究

报告了健康Ｃ５７ＢＬ小鼠血清，全血和鼠毛中９种元素含量。在３种生物样品中测定的元素以鼠毛中含量最高，血清中最低，本文讨论了小鼠和人的血清和毛发元素水平之间的关系，Ｃ５７ＢＬ小鼠作为研究元素和疾病关系的实验动物有其优点。     

Oxidative Reactions of Azines. 9. Cascade and Stage Oxidation of 1,4-Disubstituted 1,2,3,6-Tetrahydropyridines by Potassium Permanganate

A general scheme was developed for the cascade and stage oxidation of 1,4-disubstituted 1,2,3,6-tetrahydropyridines by potassium permanganate, based on the successive oxidation of the allylic triad of carbon atoms in the piperideine ring. In the case of 4-aryltetrahydropyridines 2-oxotetrahydropyridines are formed initially. 3,4-Dihydroxypiperidin-2-ones and finally 1-aminoalkan-3-ones are then formed. The oxidation of 4-methyl-substituted tetrahydropyridines to the analogous 1-aminoalkanones begins differently - with 3,4-dihydroxylation followed by lactamization of the piperidinediols.     

Oxidative reactions of azines

Oxidative coupling of 1-alkyl(benzyl)-4-(γ-pyridyl)-1,2,5,6-tetrahydropyridines with acetone in the presence of KMnO₄ follows two pathways and yields both 1-R-2-(acetylmethylene)tetrahydropyridines and 1-R-3,4-dihydroxypiperidin-2-ones. When acetonitrile is used instead of acetone, the reaction under similar conditions occurs as selective ketodihydroxylation of the starting piperideines yielding 1-R-3,4-dihydroxy-4-(γ-pyridyl)piperidin-2-ones. The molecular and crystal structures of one of these products (R=Et) was studied by X-ray diffraction analysis. For part 4, see Ref. 1 Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2020–2023, November, 1997.     

聚焦强激光束大气传输的数值模拟

 用非自适应坐标变换技术求解聚焦强激光束大气传输的热晕问题，实践表明对提高计算精度和速度十分有效，但在焦平面附近的计算，由于热晕的散焦作用，原有技术有一定困难。通过提出一种改进的非自适应坐标变换技术，克服了原有变换的缺陷，有效提高了计算精度和速度，并减少了计算机内存的占用。     

On hamiltonian cycles in the prism over the odd graphs

The Kneser graph K(n, k) has as its vertex set all k‐subsets of an n‐set and two k‐subsets are adjacent if they are disjoint. The odd graph O_k is a special case of Kneser graph when n = 2k + 1. A long standing conjecture claims that O_k is hamiltonian for all k>2. We show that the prism over O_k is hamiltonian for all k even. © 2010 Wiley Periodicals, Inc. J Graph Theory 68:177‐188, 2011     

Solubilization kinetics for polycyclic aromatic hydrocarbons transferring from a non-aqueous phase liquid to non-ionic surfactant solutions

A modified rotating disk apparatus was used to investigate the mass transfer of two polycyclic aromatic hydrocarbon (PAH) compounds, naphthalene and phenanthrene from a synthesized non-aqueous phase liquid (NAPL) comprised of hexadecane and the 2 PAHs into different non-ionic surfactant solutions. Major factors influencing the rate of solubilization of PAHs from a NAPL in micelles of different non-ionic surfactants were determined. As the surfactant concentration increased, the mass transfer coefficients for both PAHs from the NAPL decreased. The maximum rates of solubilization of the PAHs however increase with surfactant dose. The rate of solubilization was found to be limited by rates of desorption of mixed micelles from the NAPL and their rate of diffusion into the bulk solution phase. The influence of the surfactant molecular structure on the kinetics of the solubilization process was investigated. The results suggested that the length of the alkyl portion of the non-ionic surfactant and the micelle volume influenced the solubilization kinetics. The results of the investigation improve our ability to provide a rational basis for selecting the optimum surfactant and dose to enhance the solubilization of PAHs from NAPLs.     

Ruthenium(II) complexes containing 2-pyridineformamide- and 2-benzoylpyridine-derived thiosemicarbazones and PPh3: NMR and electrochemical studies of cis-trans-isomerization

[RuCl(L)(PPh(3))(2)] complexes with 2-benzoylpyridine- and 2-pyridineformamide-derived thiosemicarbazones (HL) were obtained and fully characterized. The complexes form cis-trans isomers. The cis isomer is disfavored by the sterical effect of two bulky groups close to each other whereas the trans isomer is disfavored by the electronic effect of competition of two phosphorous for pi-bonding d orbitals of the metal. Our results suggest that, although both factors may be operating simultaneously, in CH(2)Cl(2) solution the balance of these counterpoising effects favors the formation of the trans isomer.     

In vitro photodynamic inactivation of Candida spp. growth and adhesion to buccal epithelial cells

In this study, photodynamic inactivation (PDI) was used to inhibit in vitro growth and adhesion of different Candida isolates to buccal epithelial cells (BEC). Experimental conditions were optimized and 25 μM toluidine blue O (TBO) and 15 min of irradiation time by light emitting diode (LED) (energy density of 180 J/cm²) were selected due to higher reductions in cellular viability obtained after treatment. Reduction media of Log₁₀ 3.41 in viable cellular growth and media of 55% in the inhibition of adhesion to buccal epithelial cells were obtained. Two fluconazole resistant isolates were susceptible to PDI (Log₁₀ 3.54 in IB05 and Log₁₀ 1.95 in CG09) and a second session of this treatment for CG09 isolate inhibited cellular viability in 100%, without producing heat. The results permit to conclude that photodynamic inactivation under these experimental conditions would be a possible alternative approach to inhibit Candida spp. cellular growth and adhesion to buccal epithelial cells.